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Blood Clots from Vaping: Understanding the Health Risks Smoking cigarettes changes your blood chemistry. This can lead to deadly clots that cause heart attacks and block blood flow to your heart, brain, or legs. , Celebrate Heart Month and learn how to 26 Health Effects of Smoking on Your Body Smoking as well as inhaling secondhand smoke damages the heart and blood vessels. Every cigarette you smoke increases your risk of developing heart disease. Smoking speeds up the narrowing and blockage of Smoking makes your blood more likely to clot, thickens and narrows your blood vessels, and leads to the buildup of plaque all of which make you more likely to have a

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